Endocrine Abstracts

Background: Osteoporosis frequently occurs in elderly people and is commonly associated with fall and fractures which leads the increase of morbidity and mortality. Therefore, precise prediction of osteoporotic fracture is important in clinical setting. The objective of this study was to investigate the association between baseline compression fracture and trabecular bone score (TBS) and was to assess the ability of TBS to predict vertebral fragility fracture and changes of vo...

Objectives: The brain plays a major role in controlling the desire to eat. We performed a meta-analysis to assess the association of dopamine transporter (DAT)/dopamine receptor (DR) availabilities from neuroimaging studies with obesity.Methods: We performed a systematic search of MEDLINE and EMBASE for English-language publications. Data were extracted from the publications independently by two reviewers. Effect sizes were correlation coefficient betwee...

Objective: Thyroid dysfunction is frequently associated with functional disturbances of the brain. We performed a meta-analysis of previous positron emission tomography and single-photon emission computed tomography studies using a coordinate-based technique of activation-likelihood estimation (ALE) to investigate the potential background of neuropsychiatric complications in patients with hypo- and hyperthyroidism.Methods: We performed a systematic searc...

Eating behavior is determined by both homeostatic and hedonic values. We investigated the association of hedonic value with striatal dopamine transporter (DAT) availability sub-regionally. An intravenous bolus injection of 18F-FP-CIT was administered after the infusion of glucose or placebo, and the emission data were acquired over 90 mins. DAT availability, binding potential (BPND), were measured via the simplified reference tissue method. Subje...

Purpose: The purpose of this study was to evaluate the prevalence and characteristics of individuals with spine–femur bone mineral density (BMD) discordance and to examine whether trabecular bone score (TBS) is associated with major and minor BMD discordance in postmenopausal women.Methods: This retrospective study included 533 healthy postmenopausal women (median age, 60 years; range, 55–82 years) who visited our hospital for a health check-up...